Syrian Rue Seeds (Peganum harmala) – MAOI, Spiritual Use & DMT Potentiator

Syrian Rue, also known as Esfand or Harmal, is a sacred plant with a rich history in the Middle East and Central Asia. Traditionally, Syrian Rue seeds were burned as incense in Iran to purify the mind and environment, or hung in homes and vehicles in Turkey to ward off the “evil eye.”

In the modern psychonaut community, Peganum harmala is highly valued for its strong MAOI (monoamine oxidase inhibiting) properties. It is widely used as a natural alternative to Banisteriopsis caapi in “anahuasca” brews, making DMT-containing plants orally active. Syrian Rue can also enhance and prolong the effects of psilocybin mushrooms and other entheogens.

Effects of Syrian Rue (Harmala Alkaloids)

MAOI effect – prevents breakdown of neurotransmitters like DMT and serotonin
Potentiates DMT, 5-MeO-DMT, and psilocybin mushrooms
Makes inactive plants orally active
Low doses: “Harmala buzz” – a humming, vibrating body sensation
Higher doses: intensified psychedelic effects, but may cause nausea, dizziness, stomach cramps
Duration: approx. 4 hours

How to Use Syrian Rue Seeds

Raw seeds: Chew thoroughly and swallow (1–5 g depending on purpose).
Capsules: Grind seeds into powder and fill capsules for easy dosing.
Hot water infusion: Simmer crushed seeds in 150 ml water + 50 ml lemon juice for 15–30 minutes, strain, and drink. (Use 1–2 g more to compensate for loss of actives).

Dosage Guidelines

Mild: 1 g – subtle harmala buzz
Moderate: 3 g – standard MAOI dose for DMT or psilocybin potentiation
Strong: 5 g – maximum limit, often with physical discomfort

For DMT potentiation: Take 3 g seeds 15–60 minutes before consuming oral DMT. For psilocybin, Syrian Rue can make effects 1.5–2× stronger and extend duration by 1–3 hours.

Growing Syrian Rue (Peganum harmala)

Start seeds indoors in late spring in sandy soil, minimum 20°C.
Plant prefers full sun and minimal watering.
Mature plants tolerate drought and frost; leaves die back in winter while roots remain dormant.
Re-sprouts in spring for yearly growth.

Active Compounds

The primary alkaloids in Syrian Rue are harmine and harmaline, both potent reversible MAOIs responsible for its psychoactive effects.

⚠️ Safety & Warnings

Contains MAOIs – combining with certain foods (e.g., aged cheese, red wine) or substances can be dangerous.
Do not mix with alcohol, stimulants, or prescription medication.
Not suitable for minors, pregnant or breastfeeding women, or people with mental health disorders.
Always start with a low dose (1 g) to test sensitivity.
Do not drive or operate machinery under influence.

Keywords: Syrian Rue seeds, Peganum harmala, MAOI, harmala alkaloids, DMT potentiator, anahuasca, natural entheogens

Indian Spirit – Syrian Rue (Peganum Harmala) – 10G seeds